The NPM1 Antibody (N-term) from MyBioSource.com is a Rabbit Polyclonal antibody to B23, NPM, NPM1, Nucleophosmin, and nucleophosmin 1. This antibody recognizes Human, and Rat antigen. The NPM1 Antibody (N-term) has been validated for the following applications: ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
NPM1 is a ubiquitously expressed nucleolar protein that shuttles between the nucleus and cytoplasm. It is implicated in multiple functions, including ribosomal protein assembly and transport, control of centrosome duplication, and regulation of the tumor suppressor ARF. NPM1 mutations that relocalize NPM1 from the nucleus into the cytoplasm are associated with development of acute myeloid leukemia